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Numerous studies have shown that the apoptotic pathway is involved in the pathogenesis of these diseases, and it is activated only as a last resort when there is no possibility of neurons recovery ( Neurodegenerative diseases are characterized by the slow, progressive loss of neuronal cells in the central nervous system (CNS) and the aggregation of misfolded proteins (Singh et al., 2019)

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doi: 10.1016/j.jsbmb.2023.106308